CX3CR1+ macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium

@inproceedings{Manta2013CX3CR1MS,
  title={CX3CR1+ macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium},
  author={C Manta and E. E. Heupel and K Radulovic and Valerio Rossini and Natalio Garbi and Christian U Riedel and J H Niess},
  booktitle={Mucosal Immunology},
  year={2013}
}
Innate immune cells, such as intestinal epithelial cells, dendritic cells (DCs), macrophages, granulocytes, and innate lymphoid cells provide a first line of defence to enteric pathogens. To study the role of CX3CR1+ DCs and macrophages in host defence, we infected CX3CR1-GFP animals with Citrobacter rodentium. When transgenic CX3CR1-GFP animals are infected with the natural mouse pathogen C. rodentium, CX3CR1−/− animals showed a delayed clearance of C. rodentium as compared with (age- and sex… CONTINUE READING

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