CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.

@article{Colombo2013CTNNB14M,
  title={CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.},
  author={Chiara Colombo and Rosalba Miceli and Alexander J F Lazar and Federica Perrone and Raphael E Pollock and Axel le Cesne and Henk H. Hartgrink and Anne-Marie Cleton-Jansen and Julien D{\^o}mont and Judith V M G Bov{\'e}e and Sylvie Bonvalot and Dina Chelouche Lev and Alessandro Gronchi},
  journal={Cancer},
  year={2013},
  volume={119 20},
  pages={3696-702}
}
BACKGROUND A role for the serine to phenylalanine substitution at codon 45 (the S45F mutation) in the catenin (cadherin-associated protein) β-1 (CTNNB1) gene as a molecular predictor of local recurrence in patients with primary, sporadic desmoid tumor (DT) has been reported. To confirm the previous data, the authors evaluated the correlation between CTNNB1 mutation type and local recurrence in this multi-institutional, retrospective study. METHODS Patients with primary, sporadic DT who… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

Similar Papers

Loading similar papers…