CTLA-4 polymorphism and clinical outcome post allogeneic hematopoietic stem cell transplantation.

Abstract

CTLA-4 inhibitory molecule plays an important role in regulating T cell activation. It is considered a crucial element in keeping the immune balance and has been implicated in cancer, autoimmunity and transplantation immunology. Inconsistent observations are reported regarding its association with hematopoietic stem cell transplantation (HSCT). Genotyping… (More)
DOI: 10.1016/j.humimm.2013.08.002

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