CTLA-4 49 A/G dimorphism and type 1 diabetes susceptibility: a French case-control study and segregation analysis. Evidence of a maternal effect.

Abstract

Several studies have demonstrated an association of cytotoxic T lymphocyte-associated molecule 4 (CTLA-4) (IDDM 12) alanine 17 with type 1 diabetes, but we wished to study the parental effect of CTLA-4 49 A/G dimorphism in diabetic families. The CTLA-4 exon 1 polymorphism (49 A/G), HLA-DRB1 and insulin gene (INS) variable number tandem repeats (VNTR) were… (More)

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Cite this paper

@article{Fajardy2002CTLA44A, title={CTLA-4 49 A/G dimorphism and type 1 diabetes susceptibility: a French case-control study and segregation analysis. Evidence of a maternal effect.}, author={Isabelle Fajardy and Anne Vambergue and Catherine Stuckens and Jacques Weill and P M Danz{\'e} and P. Fontaine}, journal={European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics}, year={2002}, volume={29 3}, pages={251-7} }