CTF determination and correction in electron cryotomography

@inproceedings{Fernndeza2006CTFDA,
  title={CTF determination and correction in electron cryotomography},
  author={J. J. Fern{\'a}ndeza and Sheng Lia and R. A. Crowthera},
  year={2006}
}
  • J. J. Fernándeza, Sheng Lia, R. A. Crowthera
  • Published 2006
Electron cryotomography (cryoET) has the potential to elucidate the structure of complex biological specimens at molecular resolution but technical and computational improvements are still needed. This work addresses the determination and correction of the contrast transfer function (CTF) of the electron microscope in cryoET. Our approach to CTF detection and defocus determination depends on strip-based periodogram averaging, extended throughout the tilt series to overcome the low contrast… CONTINUE READING

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