CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.

@article{Lee1991CTDKL,
  title={CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.},
  author={Jeanne M. Lee and Arno L. Greenleaf},
  journal={Gene expression},
  year={1991},
  volume={1 2},
  pages={149-67}
}
We previously purified a yeast protein kinase that specifically hyperphosphorylates the carboxyl-terminal repeat domain (CTD) of RNA polymerase II largest subunit and showed that this CTD kinase consists of three subunits of 58, 38, and 32 kDa. We have now cloned, sequenced, and characterized CTK1, the gene encoding the 58 kDa alpha subunit. The CTK1 gene product contains a central domain homologous to catalytic subunits of other protein kinases, notably yeast CDC28, suggesting that the 58 kDa… CONTINUE READING

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