CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic

Abstract

CTCF is a haploinsufficient tumour suppressor gene with diverse normal functions in genome structure and gene regulation. However the mechanism by which CTCF haploinsufficiency contributes to cancer development is not well understood. CTCF is frequently mutated in endometrial cancer. Here we show that most CTCF mutations effectively result in CTCF… (More)
DOI: 10.1038/onc.2017.25

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Cite this paper

@inproceedings{Marshall2017CTCFGA, title={CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic}, author={Alan Marshall and C. G. Bailey and Karen I Champ and Melissa A Vellozzi and P O'Young and Cynthia Metierre and Y. Feng and Annora D Thoeng and Anne Richards and Uli Schmitz and Mikl{\'o}s Bir{\'o} and R. Jayasinghe and L. Ding and Lynda A. Anderson and E R Mardis and John E. J. Rasko}, booktitle={Oncogene}, year={2017} }