CT7 (MAGE-C1) antigen expression in normal and neoplastic tissues.

  title={CT7 (MAGE-C1) antigen expression in normal and neoplastic tissues.},
  author={Achim A. Jungbluth and Yao-Tseng Chen and Klaus J. Busam and Keren Coplan and Denise Kolb and Kristin Iversen and Barbara D Williamson and Frank K H van Landeghem and Elisabeth Stockert and L. John Old},
  journal={International journal of cancer},
  volume={99 6},
CT7 (MAGE-C1) is a member of the cancer testis (CT) antigen family. The present study describes the generation of CT7-33, a monoclonal antibody (MAb) to CT7, and the preliminary protein expression analysis of CT7 in normal tissues and in a limited number of neoplastic lesions. CT7-33 was effective in frozen as well as formalin-fixed, paraffin-embedded tissues, and immunohistochemistry/reverse transcriptase polymerase chain reaction (RT-PCR) co-typing demonstrated antibody specificity. CT7-33… CONTINUE READING
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