CSR, a scavenger receptor-like protein with a protective role against cellular damage causedby UV irradiation and oxidative stress.

@article{Han1998CSRAS,
  title={CSR, a scavenger receptor-like protein with a protective role against cellular damage causedby UV irradiation and oxidative stress.},
  author={Hee Jung Han and Takashi Tokino and Yasuyuki Nakamura},
  journal={Human molecular genetics},
  year={1998},
  volume={7 6},
  pages={1039-46}
}
Oxidative stress is a pathogenic condition that causes cellular damage and, in a normally functioning cell, several transcription factors respond to this threat by modulating expression of genes whose products ameliorate the altered redox status in some way. We have isolated a novel macrophage scavenger receptor-like gene, CSR (cellular stress response), whose transcription in normal fibroblasts was significantly elevated by exposure to UV radiation or hydrogen peroxide, and pre-treatment with… CONTINUE READING