CSF total tau, Aβ42 and phosphorylated tau protein as biomarkers for Alzheimer’s disease

@article{Blennow2001CSFTT,
  title={CSF total tau, Aβ42 and phosphorylated tau protein as biomarkers for Alzheimer’s disease},
  author={K Blennow and Eugeen Vanmechelen and Harald Hampel},
  journal={Molecular Neurobiology},
  year={2001},
  volume={24},
  pages={87-97}
}
With the arrival of effective symptomatic treatments and the promise of drugs that may delay progression, we now need to identify Alzheimer’s disease (AD) at an early stage of the disease. To diagnose AD earlier and more accurately, attention has been directed toward peripheral biochemical markers. This article reviews promising potential cerebrospinal fluid (CSF) biomarkers for AD focussing on their role in clinical diagnosis. In particular, two biochemical markers, CSF total tau (t-tau… CONTINUE READING
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