CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease

@article{SnchezJuan2006CSFTI,
  title={CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease},
  author={Pascual S{\'a}nchez-Juan and Ari J. Green and Anna Ladogana and Natividad Cuadrado-Corrales and R S{\'a}anchez-Valle and E. Mitrováa and Katharina Stoeck and Theodoros Sklaviadis and Jerzy Kulczycki and Klaus Hess and Monica Bodemer and Dana Slivarichov{\'a} and Albert Saiz and Miguel Calero and Loredana Ingrosso and Richard S. G. Knight and A. Cecile J. W. Janssens and Cornelia M. van Duijn and Inga Zerr},
  journal={Neurology},
  year={2006},
  volume={67},
  pages={637 - 643}
}
Objectives: To analyze the diagnostic sensitivity and specificity of various brain-derived proteins (14-3-3, Tau, neuron specific enolase [NSE], and S100b) in the CSF of patients with Creutzfeldt-Jakob disease (CJD) and to analyze biologic factors that modify these parameters. Methods: CSF was tested for 14-3-3, Tau, NSE, and S100b in 1,859 patients with sporadic, genetic, iatrogenic, and variant CJD, and in 1,117 controls. Results: The highest sensitivity was achieved for 14-3-3 and Tau in… 

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TLDR
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Cerebrospinal Fluid Markers in Sporadic Creutzfeldt-Jakob Disease
TLDR
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TLDR
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Cerebrospinal Fluid Biomarkers in the Diagnosis of Creutzfeldt-Jakob Disease in Slovak Patients: over 10-Year Period Review
TLDR
Comparing levels of cerebrospinal fluid biomarkers in Slovak population of CJD suspect cases, retrospectively in over a 10-year period shows that the total tau levels were significantly higher in CJD patients than in controls, but there was also significant difference between gCJD and sCJD (levels in cCJD were lower; p = 0.003).
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