CSF somatostatin in anorexia nervosa and bulimia: relationship to the hypothalamic pituitary-adrenal cortical axis.

@article{Kaye1988CSFSI,
  title={CSF somatostatin in anorexia nervosa and bulimia: relationship to the hypothalamic pituitary-adrenal cortical axis.},
  author={Walter H. Kaye and David Rubinow and Harry E. Gwirtsman and David Ted George and David C. Jimerson and Philip W. Gold},
  journal={Psychoneuroendocrinology},
  year={1988},
  volume={13 3},
  pages={265-72}
}
The eating disorders, anorexia nervosa and normal weight bulimia, are associated with disturbances of hypothalamic-pituitary-adrenal cortical (HPA) and growth hormone function. Because somatostatin (SRIF) is one of the neuropeptides known to modulate feeding behavior and neuroendocrine systems, we measured cerebrospinal fluid (CSF) concentrations of this peptide in patients with eating disorders. CSF SRIF concentrations in patients with anorexia nervosa, both at low weight and after weight… CONTINUE READING