CSF Protein Contents and their Roles in Brain Development

  title={CSF Protein Contents and their Roles in Brain Development},
  author={Mohammad Nabiuni and Rozmehr Shokohi and Parisa Moghaddam},
In early stages of development, the laminated structure of cerebral cortex is organized by proliferative, morphogenetic, and migratory processes. In these stages, cells within the ependymal lining of neural tube are thought to secrete embryonic cerebrospinal fluid (eCSF). As the neural tube closes, the choroid plexuses (CPs) secrete proteins such as growth factors, cytokines and morphogenes into the eCSF. The apical neuroepithelium is bathed with this fluid which plays regulatory roles in… CONTINUE READING