CSF‐1 control of C‐FMS expression in normal human bone marrow progenitors

@article{Panterne1993CSF1CO,
  title={CSF‐1 control of C‐FMS expression in normal human bone marrow progenitors},
  author={Béatrice Panterne and Y Q Zhou and Jacques A. Hatzfeld and M L Li and Jean-Pierre L{\'e}vesque and Steven C. Clark and Antoinette Hatzfeld},
  journal={Journal of Cellular Physiology},
  year={1993},
  volume={155}
}
We have previously shown (Zhou et al: Blood, 72:1870, 1988) that IL3, added with low concentrations of CSF‐1 (1 ng/ml) to normal human CD34+ enriched cells, promoted the development of various types of colonies including those containing immature monocytes. However, when high concentrations of CSF‐1 (20 ng/ml) were added alone or together with IL3, smaller colonies with mature macrophages were found. Here we show by in situ hybridization that IL3 allows the development, from CD34+ cells, of a… 
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