CRP gene is involved in the regulation of human longevity: a follow-up study in Finnish nonagenarians.

Abstract

Chronic low-grade inflammation is involved in the pathogenesis of many disease conditions in humans and it is frequently quantified by measuring the blood concentration of C-reactive protein (CRP). Here we show that the CRP concentration in old people (nonagenarians) is, at least partially, genetically determined, and that the high producer genotype is… (More)

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@article{Hurme2007CRPGI, title={CRP gene is involved in the regulation of human longevity: a follow-up study in Finnish nonagenarians.}, author={Mikko Hurme and Mika Kivim{\"a}ki and Marja I Pertovaara and Tiina T. Lehtim{\"a}ki and P{\"a}ivi Karhunen and Marika E Jylh{\"a} and Antti Hervonen and Carita M Eklund}, journal={Mechanisms of ageing and development}, year={2007}, volume={128 10}, pages={574-6} }