CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation.

@article{Kawano2005CRMP2II,
  title={CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation.},
  author={Yoji Kawano and Takeshi Yoshimura and Daisuke Tsuboi and Saeko Kawabata and Takako Kaneko-Kawano and Hiromichi Shirataki and Tadaomi Takenawa and Kozo Kaibuchi},
  journal={Molecular and cellular biology},
  year={2005},
  volume={25 22},
  pages={9920-35}
}
A neuron has two types of highly polarized cell processes, the single axon and multiple dendrites. One of the fundamental questions of neurobiology is how neurons acquire such specific and polarized morphologies. During neuronal development, various actin-binding proteins regulate dynamics of actin cytoskeleton in the growth cones of developing axons. The regulation of actin cytoskeleton in the growth cones is thought to be involved in axon outgrowth and axon-dendrite specification. However, it… CONTINUE READING
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