CRM1-mediated Recycling of Snurportin 1 to the Cytoplasm

@article{Paraskeva1999CRM1mediatedRO,
  title={CRM1-mediated Recycling of Snurportin 1 to the Cytoplasm },
  author={Efrosyni Paraskeva and Elisa Izaurralde and F. Ralf Bischoff and Jochen Huber and Ulrike Kutay and Enno Hartmann and Reinhard L{\"u}hrmann and Dirk G{\"o}rlich},
  journal={The Journal of Cell Biology},
  year={1999},
  volume={145},
  pages={255 - 264}
}
Importin beta is a major mediator of import into the cell nucleus. Importin beta binds cargo molecules either directly or via two types of adapter molecules, importin alpha, for import of proteins with a classical nuclear localization signal (NLS), or snurportin 1, for import of m3G-capped U snRNPs. Both adapters have an NH2-terminal importin beta-binding domain for binding to, and import by, importin beta, and both need to be returned to the cytoplasm after having delivered their cargoes to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 65 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 75 references

Similar Papers

Loading similar papers…