CRITICAL CARE ISSUES FOR THE NEPHROLOGIST: Low‐dose Dopamine in the Intensive Care Unit
@article{Karthik2006CRITICALCI, title={CRITICAL CARE ISSUES FOR THE NEPHROLOGIST: Low‐dose Dopamine in the Intensive Care Unit}, author={Swaminathan Karthik and Alan Lisbon}, journal={Seminars in Dialysis}, year={2006}, volume={19} }
For much of the last four decades, low‐dose dopamine has been considered the drug of choice to treat and prevent renal failure in the intensive care unit (ICU). The multifactorial etiology of renal failure in the ICU and the presence of coexisting multisystem organ dysfunction make the design and execution of clinical trials to study this problem difficult. However, in the last decade, several meta‐analyses and one large randomized trial have all shown a lack of benefit of low‐dose dopamine in…
23 Citations
Prevention of acute kidney injury and protection of renal function in the intensive care unit: update 2017
- Medicine, BiologyIntensive Care Medicine
- 2017
The results of recent randomised controlled trials have allowed the formulation of new recommendations and/or increase the strength of previous recommendations, but in many domains the available evidence remains insufficient, resulting from the limited quality of the clinical trials and the poor reporting of kidney outcomes.
Renal function and icu
- Medicine
- 2007
The use of vasoactive drugs is a pervasive practice in intensive care units, and hence, this area needs suitably powered, multi-center, randomized, placebo-controlled, double-blind studies to provide more rational indications for clinical practice.
Prevention of acute kidney injury and protection of renal function in the intensive care unit
- MedicineIntensive Care Medicine
- 2009
Recommendations for the prevention of acute kidney injury include prompt resuscitation of the circulation with special attention to providing adequate hydration whilst avoiding high-molecular-weight hydroxy-ethyl starch (HES) preparations, maintaining adequate blood pressure using vasopressors in vasodilatory shock, and using specific vasodilation under strict hemodynamic control in severe chronic renal insufficiency undergoing coronary intervention.
Pediatric Acute Kidney Injury: Focusing on Diagnosis and Management
- Medicine, Biology
- 2020
For high risk or early stage AKI patients, optimization of volume status and blood pressure, avoidance of nephrotoxins, and sufficient nutritional support are necessary, and have been demonstrated to be effective in preventing the occurrence of AKI and improving prognosis.
[Acute kidney injury].
- MedicineDeutsche medizinische Wochenschrift
- 2011
New guidelines of the "Kidney Disease: Improving Global Outcome" (KDIGO) working group standardize the definition of acute kidney injury (AKI) and acute kidney disease (AKD) allowing the assessment…
Vasopressors in Neonatal Shock
- Medicine
- 2007
As we take long strides in managing smaller and more fragile neonates, we more often come face to face w ith a lacuna in managing adequate systemic blood flow and providing circu latory support.…
Effects of low-dose dopamine on urine output in normotensive very low birth weight neonates
- MedicineJournal of Perinatology
- 2013
Low-dose dopamine use was associated with increased UOP in very low birth weight neonates, and the improvement remained statistically significant after controlling for medications, fluid intake and fluid intake.
Best practice for perioperative management of patients with cytoreductive surgery and HIPEC.
- MedicineEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
- 2017
Anaesthetic Considerations in the Perioperative Management of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
- MedicineIndian Journal of Surgical Oncology
- 2016
The present overview summarizes the challenges faced by the anaesthesiologist regarding the pathophysiological alterations during the Cytoreductive surgery and Hyperthermic intraperitoneal chemotherapy in the preoperative, intraoperative and postoperative periods.
References
SHOWING 1-10 OF 59 REFERENCES
Low-dose dopamine does not prevent acute renal failure in patients with septic shock and oliguria. NORASEPT II Study Investigators.
- MedicineThe American journal of medicine
- 1999
Low-dose dopamine in patients with early renal dysfunction: a placebo-controlled randomised trial
- Medicine, BiologyThe Lancet
- 2000
Use of dopamine in acute renal failure: A meta-analysis
- MedicineCritical care medicine
- 2001
The use of low-dose dopamine for the treatment or prevention of acute renal failure cannot be justified on the basis of available evidence and should be eliminated from routine clinical use.
Is the administration of dopamine associated with adverse or favorable outcomes in acute renal failure? Auriculin Anaritide Acute Renal Failure Study Group.
- Medicine, BiologyThe American journal of medicine
- 1996
A comparison between fenoldopam and low-dose dopamine in early renal dysfunction of critically ill patients*
- MedicineCritical care medicine
- 2006
In critically ill patients, a continuous infusion of fenoldopam at 0.1 &mgr;g/kg/min does not cause any clinically significant hemodynamic impairment and improves renal function compared with renal dose dopamine, and in the setting of acute early renal dysfunction, the attempt to reverse renal hypoperfusion with fen oldopam is more effective than with low-dose dopamine.
Meta-Analysis: Low-Dose Dopamine Increases Urine Output but Does Not Prevent Renal Dysfunction or Death
- MedicineAnnals of Internal Medicine
- 2005
A systematic review and meta-analysis of low-dose dopamine was conducted by using a comprehensive search strategy to determine its effect on a broad range of clinical and renal physiologic outcomes and adverse events.
Lack of renoprotective effects of dopamine and furosemide during cardiac surgery.
- MedicineJournal of the American Society of Nephrology : JASN
- 2000
It was shown that continuous infusion of dopamine for renal protection was ineffective and was not superior to placebo in preventing postoperative dysfunction after cardiac surgery and furosemide was associated with the highest rate of renal impairment.
Physiologic Impact of Low-Dose Dopamine on Renal Function in the Early Post Renal Transplant Period
- MedicineTransplantation
- 2005
LDD significantly increases ERPF, UFR, CC, and tUNa in the transplanted allograft kidney treated with cyclosporine immunosuppression in the early posttransplant period.
Does dopamine administration in shock influence outcome? Results of the Sepsis Occurrence in Acutely Ill Patients (SOAP) Study*
- MedicineCritical care medicine
- 2006
It is suggested that dopamine administration may be associated with increased mortality rates in shock, and there is a need for a prospective study comparing dopamine with other catecholamines in the management of circulatory shock.
Dopamine clearance in critically ill patients
- Medicine, BiologyIntensive Care Medicine
- 1998
Plasma dopamine clearance is lower in critically ill patients and there is a large interindividual variation, therefore it is impossible to predict the plasma level from the infusion rate, and the concept of a selective renovascular low-dose dopamine infusion is invalid in critical ill patients.