CRISPR transcript processing: a mechanism for generating a large number of small interfering RNAs

@inproceedings{Djordjevic2012CRISPRTP,
  title={CRISPR transcript processing: a mechanism for generating a large number of small interfering RNAs},
  author={Marko Djordjevic and Magdalena Djordjevic and Konstantin Severinov},
  booktitle={Biology Direct},
  year={2012}
}
CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated sequences) is a recently discovered prokaryotic defense system against foreign DNA, including viruses and plasmids. CRISPR cassette is transcribed as a continuous transcript (pre-crRNA), which is processed by Cas proteins into small RNA molecules (crRNAs) that are… CONTINUE READING