CRISPR interference-mediated metabolic engineering of Corynebacterium glutamicum for homo-butyrate production.

Combinatorial metabolic engineering enabled the development of efficient microbial cell factories for modulating gene expression to produce desired products. Here, we report the combinatorial metabolic engineering of Corynebacterium glutamicum to produce butyrate by introducing a synthetic butyrate pathway including phosphotransferase and butyrate kinase… CONTINUE READING