Modified Nucleosides, Nucleotides and Nucleic Acids via Click Azide-Alkyne Cycloaddition for Pharmacological Applications
- Chemistry, BiologyMolecules
This review provides an overview of the most recent works related to the use of click chemistry methodology in the field of nucleosides, nucleotides and nucleic acids for pharmacological applications.
Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing
- Biology, EngineeringJournal of Nanobiotechnology
The recent advances in stimuli-responsive nanoformulations for CRISPR-Cas9 delivery are overviewed, the rationale of stimuli and formulation designs are highlighted, and their biomedical applications are summarized.
The four Fs of the Knowledge-Based BioEconomy—an homage to Christian Patermann
- EFB Bioeconomy Journal
The Emergence of Genome Editing—Innovation Network Dynamics of Academic Publications, Patents, and Business Activities
- EconomicsFrontiers in Bioengineering and Biotechnology
Transformative societal change can both be triggered and influenced by both macro-level political means and the emergence of technologies. Key enabling technologies and therein biotechnology hold the…
Biosafety of Genome Editing Applications in Plant Breeding: Considerations for a Focused Case-Specific Risk Assessment in the EU
- Environmental ScienceBiotech (Basel (Switzerland))
An intensely debated question is whether or how a mandatory environmental risk assessment (ERA) should be conducted for plants obtained through novel genomic techniques, including genome editing…
Current status and prospects of plant genome editing in Australia
- BiologyIn vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association
The present review discusses the current status and prospects of plant genome editing in Australia by highlighting several species of interest, and discusses the priorities and potential of CRISPR-Cas, as well as the remaining challenges.
Cell‐Based Delivery Systems: Emerging Carriers for Immunotherapy
- BiologyAdvanced Functional Materials
An overview of the fundamentals and design principles of cell-based delivery systems followed by a perspective that includes the most recent advances of various cells as delivery carriers, with a special focus on the implications of cell‐ based delivery systems for immunotherapy is offered.
Contribution of advanced fluorescence nano microscopy towards revealing mitotic chromosome structure.
- BiologyChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology
Both FLIM and SRM have been lacking in the application of chromosome research while SRM has been successfully applied although not widely and the future prospects of how advancements in new technologies can contribute in the field of chromosome science are highlighted.
Evolution and Biology of CRISPR System: A New Era Tool for Genome Editing in Plants
The evolution of CRISPR along the time and recent advances in understanding the vivid mechanism by which Cas proteins respond to foreign nucleic acids are discussed and how these systems have been harnessed for precise genome manipulation in plants.