CRISPR-Cas systems for editing, regulating and targeting genomes

Abstract

Targeted genome editing using engineered nucleases has rapidly gone from being a niche technology to a mainstream method used by many biological researchers. This widespread adoption has been largely fueled by the emergence of the clustered, regularly interspaced, short palindromic repeat (CRISPR) technology, an important new approach for generating RNA… (More)
DOI: 10.1038/nbt.2842

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