CRISPR-Cas: A revolution in genome engineering

@inproceedings{Riddihough2014CRISPRCasAR,
  title={CRISPR-Cas: A revolution in genome engineering},
  author={Guy Riddihough},
  year={2014}
}
Genome Engineering The ability to engineer genomic DNA in cells and organisms easily and precisely will have major implications for basic biology research, medicine, and biotechnology. Doudna and Charpentier review the history of genome editing technologies, including oligonucleotide coupled to genome cleaving agents that rely on endogenous repair and recombination systems to complete the targeted changes, self-splicing introns, and zinc-finger nucleases and TAL effector nucleases. They then… CONTINUE READING
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