CRISPR/Cas9 Technology-Based Xenograft Tumors as Candidate Reference Materials for Multiple EML4-ALK Rearrangements Testing.

@article{Peng2017CRISPRCas9TX,
  title={CRISPR/Cas9 Technology-Based Xenograft Tumors as Candidate Reference Materials for Multiple EML4-ALK Rearrangements Testing.},
  author={Rongxue Peng and Rui Zhang and Guigao Lin and Xin Yang and Ziyang Li and Kuo Zhang and Jiawei Zhang and Jinming Li},
  journal={The Journal of molecular diagnostics : JMD},
  year={2017},
  volume={19 5},
  pages={766-775}
}
The echinoderm microtubule-associated protein-like 4 and anaplastic lymphoma kinase (ALK) receptor tyrosine kinase (EML4-ALK) rearrangement is an important biomarker that plays a pivotal role in therapeutic decision making for non-small-cell lung cancer (NSCLC) patients. Ensuring accuracy and reproducibility of EML4-ALK testing by fluorescence in situ… CONTINUE READING