CRHR1 links peripuberty stress with deficits in social and stress-coping behaviors.

@article{Veenit2014CRHR1LP,
  title={CRHR1 links peripuberty stress with deficits in social and stress-coping behaviors.},
  author={Vandana Veenit and Orbicia Riccio and Carmen Sandi},
  journal={Journal of psychiatric research},
  year={2014},
  volume={53},
  pages={1-7}
}
Stressful life events during childhood and adolescence are important risk factors for the development of psychopathologies later in life. The corticotropin releasing hormone (CRH) and the CRH receptor 1 (CRHR1) have been implicated in the link between early life adversity and adult anxiety and depression, with rodent studies identifying the very early postnatal period as highly susceptible to this programming. Here, we investigated whether stress exposure during the peripubertal period… CONTINUE READING
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Forebrain CRF ( 1 ) modulates early - life stress - programmed cognitive de fi cits

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