CRF receptor type 1 (but not type 2) located within the amygdala plays a role in the modulation of anxiety in mice exposed to the elevated plus maze.

@article{Cipriano2016CRFRT,
  title={CRF receptor type 1 (but not type 2) located within the amygdala plays a role in the modulation of anxiety in mice exposed to the elevated plus maze.},
  author={Ana Cl{\'a}udia Cipriano and Karina Santos Gomes and Ricardo Luiz Nunes-de-Souza},
  journal={Hormones and behavior},
  year={2016},
  volume={81},
  pages={59-67}
}
The amygdala (Amy) is an important center that processes threatening stimuli. Among the neurotransmitters implicated in the control of emotional states, the corticotrophin releasing factor (CRF) is an important modulator, acting at CRF1 and CRF2 receptors. Few studies have investigated the role of CRF and its receptors in the Amy on anxiety in mice. Here… CONTINUE READING