CRF ligands via Suzuki and Negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine.

@article{Arvanitis2003CRFLV,
  title={CRF ligands via Suzuki and Negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine.},
  author={Argyrios G Arvanitis and Charles R Arnold and Lawrence W. Fitzgerald and William E Frietze and Richard E. Olson and Paul J. Gilligan and David W. Robertson},
  journal={Bioorganic & medicinal chemistry letters},
  year={2003},
  volume={13 2},
  pages={289-91}
}
A series of imidazo[4,5-b]pyridines with a 7-(3-pyridyl) substituent is described as high affinity CRF receptor ligands. Individual analogues were synthesized from key intermediates obtained via palladium-catalyzed coupling of 3-pyridyl zinc or boronic acid organometallic intermediates with 2-benzyloxy-4-chloro-3-nitropyridine 12.