CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesis

@inproceedings{Oh2013CREBAF,
  title={CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesis},
  author={Kyoung-Jin Oh and Hye Sook Han and Min-Jung Kim and Seung-Hoi Koo},
  booktitle={BMB reports},
  year={2013}
}
Liver plays a major role in maintaining glucose homeostasis in mammals. Under fasting conditions, hepatic glucose production is critical as a source of fuel to maintain the basic functions in other tissues, including skeletal muscle, red blood cells, and the brain. Fasting hormones glucagon and cortisol play major roles during the process, in part by activating the transcription of key enzyme genes in the gluconeogenesis such as phosphoenol pyruvate carboxykinase (PEPCK) and glucose 6… CONTINUE READING