CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide

Abstract

Polymorphonuclear leukocytes (PMN) from three patients deficient in the CD18 family of receptors (LFA-1, CR3, and p150,95) exhibited an inability to bind erythrocytes coated with C3bi or bacterial LPS. These observations confirm that the CD18 family, and CR3 in particular, can bind the structurally dissimilar molecules C3bi and LPS. Further studies showed… (More)

Topics

5 Figures and Tables

Cite this paper

@article{Wright1989CR3E, title={CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide}, author={S. D. Wright and S M Levin and Michelle Jong and Zave Chad and Lynda Kabbash}, journal={The Journal of Experimental Medicine}, year={1989}, volume={169}, pages={175 - 183} }