COX-2 overexpression in canine tumors: potential therapeutic targets in oncology.

Abstract

Cyclooxygenases catalyze the initial, rate-limiting steps of prostaglandin synthesis from arachidonic acid. Two isoforms of this enzyme exist in mammalian and avian species: COX-1 and COX-2. COX-1 is constitutively expressed and is the major isoform of gastrointestinal tissue. COX-2 is induced in response to inflammatory stimuli. COX-2 has been implicated… (More)
DOI: 10.14670/HH-20.1309

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Cite this paper

@article{Spugnini2005COX2OI, title={COX-2 overexpression in canine tumors: potential therapeutic targets in oncology.}, author={Enrico Pierluigi Spugnini and Alessandro Porrello and Gennaro Citro and Alfonso Baldi}, journal={Histology and histopathology}, year={2005}, volume={20 4}, pages={1309-12} }