COX-2 inhibition decreases VEGF expression and alveolar bone loss during the progression of experimental periodontitis in rats.

Abstract

BACKGROUND Vascular endothelial growth factor (VEGF) is a macromolecule of importance in inflammation that has been implicated in periodontitis. The aims of this study were to investigate VEGF expression during the progression of periodontal disease and to evaluate the effect of a preferential cyclooxygenase (COX)-2 inhibitor meloxicam on VEGF expression… (More)
DOI: 10.1902/jop.2008.070411

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