COVID-19 vaccines poised for launch, but impact on pandemic unclear.

  title={COVID-19 vaccines poised for launch, but impact on pandemic unclear.},
  author={E. Dolgin},
  journal={Nature biotechnology},
  • E. Dolgin
  • Published 2020
  • Medicine, Geography
  • Nature biotechnology
Ongoing Clinical Trials of Vaccines to Fight against COVID-19 Pandemic
The ongoing clinical trial landscape of the COVID-19 as well as repurposed vaccines, an insight into the current status of the available antigenic epitopes for SARS-CoV-2 and different types of vaccine platforms of CO VID-19 vaccines has been discussed. Expand
Development of thermostable vaccine adjuvants
This narrative review summarizes the current status of thermostable vaccine adjuvant development and looks forward to the next potential developments in the field. Expand
Does COVID-19 Vaccination Warrant the Classical Principle “ofelein i mi vlaptin”?
This review critically summarizes existing evidence and queries regarding SARS-CoV-2 vaccines to motivate scientists’ and clinicians’ interest for an optimal, individualized, and holistic management of this unprecedented pandemic. Expand
Management of COVID-19: current status and future prospects
The management strategies including Prevention of spread, prophylaxis, vaccinations, and treatment for COVID-19 are discussed, and analysis of vaccine development status and performance are also briefly discussed. Expand
Money is not everything: experimental evidence that payments do not increase willingness to be vaccinated against COVID-19
An experiment investigating the impact of payments and the communication of individual and prosocial benefits of high vaccination rates on vaccination intentions revealed that none of these interventions or their combinations increased willingness to be vaccinated shortly after a vaccine becomes available. Expand
The century of mRNA vaccines: COVID-19 vaccines and allergy
Ortega Rodríguez NR1,5, Audícana Berasategui MT2,5, de la Hoz Caballer B3,5, Valero Santiago A4,5 1Servicio de Alergia e Inmunología Clínica, HU de Gran Canaria Dr Negrín ULPGC, Las Palmas, SpainExpand
Will the mRNA Vaccines Interfere with One’s DNA?
The unique attributes of mRNA vaccines and current challenges and expectations within the context of the COVID-19 pandemic are discussed. Expand
mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
To improve the stability of mRNA-LNP vaccines, optimization of the mRNA nucleotide composition should be prioritized and a better understanding of the milieu the mRNA is exposed to in the core of LNPs may help to rationalize adjustments to the LNP structure to preserve mRNA integrity. Expand
COVID-19 update: the first 6 months of the pandemic
The role of the pathogen, the host and the environment along with the possible role of diabetes is examined, which is useful in the current COVID-19 pandemic and in a very distant future when another pandemic might arise. Expand
Resources, Production Scales and Time Required for Producing RNA Vaccines for the Global Pandemic Demand
The techno-economic feasibility of producing RNA vaccines for the demand associated with a global vaccination campaign is assessed for three messenger RNA and one self-amplifying RNA (saRNA) vaccines, all currently under clinical development, as well as for a hypothetical next-generation saRNA vaccine. Expand