COVID-19 reinfection: a rapid systematic review of case reports and case series

  title={COVID-19 reinfection: a rapid systematic review of case reports and case series},
  author={Jingzhou Wang and Christopher J Kaperak and Toshiro Sato and Atsushi Sakuraba},
  journal={Journal of Investigative Medicine},
  pages={1253 - 1255}
The COVID-19 pandemic has infected millions of people worldwide and many countries have been suffering from a large number of deaths. Acknowledging the ability of SARS-CoV-2 to mutate into distinct strains as an RNA virus and investigating its potential to cause reinfection is important for future health policy guidelines. It was thought that individuals who recovered from COVID-19 generate a robust immune response and develop protective immunity; however, since the first case of documented… Expand
4 Citations
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This review summarizes the main knowledge that is known about the humoral immune response during COVID-19 disease or after vaccination and should help to optimize vaccination strategies and public health decisions. Expand
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Great progress has been made over the past 18 months in scientific understanding of the biology, epidemiology and pathogenesis of SARS-CoV-2. Extraordinary advances have been made in vaccineExpand
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A workflow for whole-genome sequencing with antigen test-derived swabs as an input rather than nasopharyngeal swabs is developed and it is demonstrated that whole- genome sequencing from antigen tests is feasible and yields similar results from RT-PCR-based assays utilizing a swab in viral transport media. Expand
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A rapid decline of short-term immune response in the HCWs after the SV vaccination indicates the need for a vaccine booster, particularly during the ongoing spreading of the SAR-CoV-2 variants of concern. Expand


COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing
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The results suggest SARS-CoV-2 may continue to circulate among the human populations despite herd immunity due to natural infection or vaccination, and further studies of patients with re-infection will shed light on protective correlates important for vaccine design. Expand
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Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneity
The present method of genome annotation employed at this early pandemic stage could be a promising tool for monitoring and tracking the continuously evolving pandemic situation, the associated genetic variants, and their implications for the development of effective control and prophylaxis strategies. Expand
Role of antibody-dependent enhancement (ADE) in the virulence of SARS-CoV-2 and its mitigation strategies for the development of vaccines and immunotherapies to counter COVID-19
The present mini-review aims to address the phenomenon of ADE of SARS-CoV-2 through the lessons learned from SARS -CoV and MERS- coV and ways to mitigate them so as to develop better vaccines and immunotherapeutics against Sars-Cov-2. Expand
Do antibody positive healthcare workers have lower SARS-CoV-2 infection rates than antibody negative healthcare workers? Large multi-centre prospective cohort study (the SIREN study), England: June to November 2020
A prior history of SARS-CoV-2 infection was associated with an 83% lower risk of infection, with median protective effect observed five months following primary infection, which is the minimum likely effect as seroconversions were not included. Expand
Covid-19: New coronavirus variant is identified in UK
England’s health secretary, Matt Hancock, has told parliament that a new variant of covid-19 has been identified and may be driving infections in the south east, leading to headlines about “mutantExpand
Positive RT-PCR Test Results in Patients Recovered From COVID-19.
This case series describes reverse transcriptase–polymerase chain reaction (RT-PCR) test results in 4 health professionals discharged from hospitalization or quarantine after 2 negative RT-PCR testExpand
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