COUP-TF interacting protein 2 represses the initial phase of HIV-1 gene transcription in human microglial cells

@article{Marban2005COUPTFIP,
  title={COUP-TF interacting protein 2 represses the initial phase of HIV-1 gene transcription in human microglial cells},
  author={C{\'e}line Marban and Laetitia Redel and Stella Suzanne and Carine Van Lint and Dominique Lecestre and Sylvette Chasserot-Golaz and Mark E Leid and Dominique Aunis and Evelyne Schaeffer and Olivier Rohr},
  journal={Nucleic Acids Research},
  year={2005},
  volume={33},
  pages={2318 - 2331}
}
Human immunodeficiency virus type 1 (HIV-1) gene transcription is characterized by two temporally distinct phases. While the initial phase relies solely on cellular transcription factors, the subsequent phase is activated by the viral Tat transactivator. We have previously reported that the subsequent phase of viral gene transcription can be repressed by the chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2 (CTIP2) in human microglial cells [O. Rohr, D… CONTINUE READING

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