Pharmacokinetic and pharmacodynamic equivalence of Biocon's biosimilar Insulin 70/30 with US‐licensed HUMULIN® 70/30 formulation in healthy subjects: Results from the RHINE‐3 (Recombinant Human INsulin Equivalence‐3) study
- Biology, MedicineDiabetes, obesity & metabolism
To establish the pharmacokinetic (PK) and pharmacodynamic (PD) equivalence of proposed biosimilar insulin 70/30 (Biocon's Insulin‐70/30) and HUMULIN® 70/30 (HUMULIN‐70/30; Eli Lilly and Company, IN).
Pricing for Medicine Innovation: A Regulatory Approach to Support Drug Development and Patient Access
The United States represents the world’s largest market for pharmaceutical drugs. It is also the only advanced economy in the world that does not regulate drug prices. There is no upper threshold for…
Public Perspectives on Anti-Diabetic Drugs: Exploratory Analysis of Twitter Posts
- Medicine, Political ScienceJMIR diabetes
This study suggests that there is a fear of not having access to anti-diabetic drugs due to cost or physical availability and highlights the impact of the sacrifices made to access anti-Diabetic drugs.
Analysis of Diabetes Apps to Assess Privacy-Related Permissions: Systematic Search of Apps
- Medicine, Computer ScienceJMIR diabetes
Assessing the levels of privacy of mobile apps for diabetes to contribute to the raising of awareness of privacy issues for app users, developers, and governmental data protection regulators confirms the necessity of educating patients and health care providers and raising their awareness regarding the privacy aspects of diabetes apps.
Open-Source Technology for Real-Time Continuous Glucose Monitoring in the Neonatal Intensive Care Unit: Case Study in a Neonate With Transient Congenital Hyperinsulinism
- MedicineJournal of medical Internet research
Off-label use of real-time continuous glucose monitoring in a newborn with prolonged hypoglycemia secondary to transient congenital hyperinsulinism during the perinatal period and the use of an open-source app for glucose monitoring is described.
“Life or death”: Experiences of insulin insecurity among adults with type 1 diabetes in the United States
- MedicineSSM - population health
Profits, Innovation and Financialization in the Insulin Industry
The list prices of analogue insulin medicines in the United States have soared during the past decade. In the wake of high-profile cases of prescription medicine “price-gouging”, such as Mylan’s…
SHOWING 1-10 OF 34 REFERENCES
Cost-Related Insulin Underuse Among Patients With Diabetes
- MedicineJAMA internal medicine
This survey study examines the association of higher insulin costs with nonadherence in patients with diabetes with a history of type 2 diabetes and finds that insulin costs are higher when patients do not follow treatment.
Production costs and potential prices for biosimilars of human insulin and insulin analogues
- MedicineBMJ Global Health
Treatment with biosimilar RHI and insulin NPH could cost less than US$72 per year and with insulin analogues ≤US$133 per year, and widespread availability at estimated prices may allow substantial savings globally.
Evidence and AIDS activism: HIV scale-up and the contemporary politics of knowledge in global public health
- Political ScienceGlobal public health
What new forms of evidence and activism will be required to address the challenges of the scaling-up era of HIV treatment and prevention are examined.
Association of Insulin Pump Therapy vs Insulin Injection Therapy With Severe Hypoglycemia, Ketoacidosis, and Glycemic Control Among Children, Adolescents, and Young Adults With Type 1 Diabetes
Among young patients with type 1 diabetes, insulin pump therapy, compared with insulin injection therapy, was associated with lower risks of severe hypoglycemia and diabetic ketoacidosis and with better glycemic control during the most recent year of therapy.
Research electronic data capture (REDCap) - A metadata-driven methodology and workflow process for providing translational research informatics support
- Computer ScienceJ. Biomed. Informatics
Constraints and challenges in access to insulin: a global perspective.
- Medicine, Political ScienceThe lancet. Diabetes & endocrinology
Insulin: discovery and controversy.
- MedicineClinical chemistry
Their experiments produced an extract of pancreas that reduced the hyperglycemia and glycosuria in dogs made diabetic by the removal of their pancreases, and a procedure for extraction from the entire Pancreas without the need for duct ligation, which was successful for treating humans with diabetes.
Reduction in hemoglobin A1C with real-time continuous glucose monitoring: results from a 12-week observational study.
- MedicineDiabetes technology & therapeutics
This observational study showed that home use of real-time GCM was safe and well tolerated and associated with a clinically and statistically significant reduction in HbA1c.