COS1, a two-component histidine kinase that is involved in hyphal development in the opportunistic pathogen Candida albicans.

Abstract

Two-component histidine kinases recently have been found in eukaryotic organisms including fungi, slime molds, and plants. We describe the identification of a gene, COS1, from the opportunistic pathogen Candida albicans by using a PCR-based screening strategy. The sequence of COS1 indicates that it encodes a homolog of the histidine kinase Nik-1 from the… (More)

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@article{Alex1998COS1AT, title={COS1, a two-component histidine kinase that is involved in hyphal development in the opportunistic pathogen Candida albicans.}, author={Leesha Alex and Christopher T. Korch and Claude P. Selitrennikoff and M. I. Simon}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1998}, volume={95 12}, pages={7069-73} }