CORRIGENDUM: Non-invasive airway health assessment: Synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo

@inproceedings{Donnelley2014CORRIGENDUMNA,
  title={CORRIGENDUM: Non-invasive airway health assessment: Synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo},
  author={Martin Donnelley and Kaye Susannah Morgan and Karen K. W. Siu and Nigel Farrow and Charlene S. Stahr and Richard C. Boucher and Andreas Fouras and D Willams Parsons},
  booktitle={Scientific reports},
  year={2014}
}
To determine the efficacy of potential cystic fibrosis (CF) therapies we have developed a novel mucociliary transit (MCT) measurement that uses synchrotron phase contrast X-ray imaging (PCXI) to non-invasively measure the transit rate of individual micron-sized particles deposited into the airways of live mice. The aim of this study was to image changes in MCT produced by a rehydrating treatment based on hypertonic saline (HS), a current CF clinical treatment. Live mice received HS containing a… CONTINUE READING
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