COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin

Abstract

14 The COPI coat forms transport vesicles from the Golgi complex and plays a poorly defined role 15 in endocytic trafficking. Here we show that COPI binds K63-linked polyubiquitin and this 16 interaction is crucial for trafficking of a ubiquitinated yeast SNARE (Snc1). Snc1 is a v-SNARE 17 that drives fusion of exocytic vesicles with the plasma membrane… (More)

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