COPD: epidemiology, prevalence, morbidity and mortality, and disease heterogeneity.

@article{Mannino2002COPDEP,
  title={COPD: epidemiology, prevalence, morbidity and mortality, and disease heterogeneity.},
  author={David M Mannino},
  journal={Chest},
  year={2002},
  volume={121 5 Suppl},
  pages={121S-126S}
}
COPD continues to cause a heavy health and economic burden both in the United States and around the world. Some of the risk factors for COPD are well-known and include smoking, occupational exposures, air pollution, airway hyperresponsiveness, asthma, and certain genetic variations, although many questions, such as why < 20% of smokers develop significant airway obstruction, remain. Precise definitions of COPD vary and are frequently dependent on an accurate diagnosis of the problem by a… CONTINUE READING
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