COPD: current therapeutic interventions and future approaches.

@article{Barnes2005COPDCT,
  title={COPD: current therapeutic interventions and future approaches.},
  author={Peter J Barnes and Robert Andrew Stockley},
  journal={The European respiratory journal},
  year={2005},
  volume={25 6},
  pages={1084-106}
}
Although long-acting bronchodilators have been an important advance for the management of chronic obstructive pulmonary disease (COPD), these drugs do not deal with the underlying inflammatory process. No currently available treatments reduce the progression of COPD or suppress the inflammation in small airways and lung parenchyma. Several new treatments that target the inflammatory process are now in clinical development. Some therapies, such as chemokine antagonists, are directed against the… CONTINUE READING
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A mechanism of corticosteroid resistance in COPD: inactivation of histone deacetylase

  • PJ Barnes, K Ito, IM. Adcock
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