COPD, bone metabolism, and osteoporosis.

  title={COPD, bone metabolism, and osteoporosis.},
  author={An Lehouck and Steven Boonen and Marc Decramer and Wim Janssens},
  volume={139 3},
COPD and osteoporosis are strongly associated because of common risk factors such as age, smoking, and inactivity. In addition, COPD-related systemic inflammation, vitamin D deficiency, and the use of systemic corticosteroids enhance ongoing bone destruction. Osteoporosis, in turn, may cause fragility fractures, which further impair mobility and increase morbidity and mortality. Vertebral compression fractures and rib cage fractures in patients with COPD may also reduce pulmonary function or… CONTINUE READING
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