• Corpus ID: 29956911

COMTAN ® ( entacapone ) Tablets Rx only Prescribing Information DESCRIPTION

@inproceedings{2010COMTAN,
  title={COMTAN {\textregistered} ( entacapone ) Tablets Rx only Prescribing Information DESCRIPTION},
  author={},
  year={2010}
}
  • Published 2010
  • Chemistry
Entacapone is an inhibitor of catechol-O-methyltransferase (COMT), used in the treatment of Parkinson’s Disease as an adjunct to levodopa/carbidopa therapy. It is a nitrocatechol-structured compound with a relative molecular mass of 305.29. The chemical name of entacapone is (E)-2-cyano­ 3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide. Its empirical formula is C14H15N3O5 and its structural formula is: 
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Comtan (entacapone) tablets are manufactured by Orion Corporation, Orion Pharma (Espoo, Finland) and marketed by Novartis Pharmaceuticals Corporation
  • 2010
Store at 25°C (77°F) excursions permitted to 15°-30°C (59°-86°F)
    See USP Controlled Room Temperature