COLIA1 polymorphism contributes to bone mineral density to assess prevalent wrist fractures.

@article{Weichetova2000COLIA1PC,
  title={COLIA1 polymorphism contributes to bone mineral density to assess prevalent wrist fractures.},
  author={Marketa Weichetova and Jan J. {\vS}těp{\'a}n and Dana Michalsk{\'a} and Thomas Haas and Huibert A. P. Pols and Andr{\'e} G. Uitterlinden},
  journal={Bone},
  year={2000},
  volume={26 3},
  pages={287-90}
}
Wrist fractures associated with postmenopausal women are only partially explained by osteoporosis. Recent studies have shown that polymorphism of an Spl binding site in the first intron of the collagen I alpha 1 gene (COLIA1) may determine risk for vertebral and nonvertebral fractures in post-menopausal women independent of bone mass. We investigated the relationship between the COLIA1 polymorphism, lumbar spine and femoral neck bone mineral density (BMD), ultrasound stiffness of the heel… CONTINUE READING
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