COCH transgene expression in cultured human trabecular meshwork cells and its effect on outflow facility in monkey organ cultured anterior segments.

@article{Lee2010COCHTE,
  title={COCH transgene expression in cultured human trabecular meshwork cells and its effect on outflow facility in monkey organ cultured anterior segments.},
  author={Eun Suk Lee and B'ann T Gabelt and Jennifer A. Faralli and Donna Peters and Curtis R. Brandt and Paul L. Kaufman and Sanjoy K Bhattacharya},
  journal={Investigative ophthalmology & visual science},
  year={2010},
  volume={51 4},
  pages={2060-6}
}
Purpose. To determine the effects of COCH transgene expression on cultured human trabecular meshwork (HTM) cell morphology and on outflow facility (OF) in monkey organ cultured anterior segments (MOCAS). Methods. An adenoviral (Ad) vector expressing both cochlin (COCH) and green fluorescent protein (GFP) (AdCOCHGFP) or GFP alone (AdGFP) was used to transduce cultured HTM cells (multiplicity of transduction, 2.8 and 28). COCH transgene expression in transduced HTM cells and the culture medium… CONTINUE READING

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Self-complementary AAV virus (scAAV) override AAV transduction inability and confer long-term expression to the trabecular meshwork of living animals

  • LK Buie, C Rasmussen, EC Porterfield
  • Invest Ophthalmol Vis Sci
  • 2010

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