CO and CO-releasing molecules (CO-RMs) in acute gastrointestinal inflammation.

Abstract

Carbon monoxide (CO) is enzymatically generated in mammalian cells alongside the liberation of iron and the production of biliverdin and bilirubin. This occurs during the degradation of haem by haem oxygenase (HO) enzymes, a class of ubiquitous proteins consisting of constitutive and inducible isoforms. The constitutive HO2 is present in the… (More)
DOI: 10.1111/bph.12632

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