CNTNAP2 is disrupted in a family with Gilles de la Tourette syndrome and obsessive compulsive disorder.

@article{Verkerk2003CNTNAP2ID,
  title={CNTNAP2 is disrupted in a family with Gilles de la Tourette syndrome and obsessive compulsive disorder.},
  author={Annemieke J M H Verkerk and Carol A Mathews and Marijke N. Joosse and Bert H J Eussen and Peter Heutink and Ben A. Oostra},
  journal={Genomics},
  year={2003},
  volume={82 1},
  pages={1-9}
}
Gilles de la Tourette syndrome (GTS) is a sporadic or inherited complex neuropsychiatric disorder characterized by involuntary motor and vocal tics. There is comorbidity with disorders like obsessive compulsive disorder and attention deficit hyperactivity disorder. Until now linkage analysis has pointed to a number of chromosomal locations, but has failed to identify a clear candidate gene(s). We have investigated a GTS family with a complex chromosomal insertion/translocation involving… CONTINUE READING
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