CNS or bone marrow involvement as risk factors for poor survival in post-transplantation lymphoproliferative disorders in children after solid organ transplantation.

@article{Maecker2007CNSOB,
  title={CNS or bone marrow involvement as risk factors for poor survival in post-transplantation lymphoproliferative disorders in children after solid organ transplantation.},
  author={Britta Maecker and Thomas Jack and Martin Zimmermann and Hashim Abdul-Khaliq and Martin M. Burdelski and Alexandra Th Fuchs and Peter F. Hoyer and Sabine Koepf and U. Kr{\"a}mer and Guido F. Laube and D E M{\"u}ller-wiefel and Heinrich Netz and Martin Pohl and Burkhard Toenshoff and H Wagner and Michael Wallot and Karl Welte and Michael Melter and Gisela Offner and Christoph Klein},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2007},
  volume={25 31},
  pages={4902-8}
}
PURPOSE To identify prognostic factors of survival in pediatric post-transplantation lymphoproliferative disorder (PTLD) after solid organ transplantation. PATIENTS AND METHODS A multicenter, retrospective case analysis of 55 pediatric solid organ graft recipients (kidney, liver, heart/lung) developing PTLD were reported to the German Pediatric-PTLD registry. Patient charts were analyzed for tumor characteristics (histology, immunophenotypes, cytogenetics, Epstein-Barr virus [EBV] detection… CONTINUE READING
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