CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

@article{Fitch2008CNSIG,
  title={CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure},
  author={Michael T. Fitch and Jerry Silver},
  journal={Experimental Neurology},
  year={2008},
  volume={209},
  pages={294-301}
}
Spinal cord and brain injuries lead to complex cellular and molecular interactions within the central nervous system in an attempt to repair the initial tissue damage. Many studies have illustrated the importance of the glial cell response to injury, and the influences of inflammation and wound healing processes on the overall morbidity and permanent disability that result. The abortive attempts of neuronal regeneration after spinal cord injury are influenced by inflammatory cell activation… CONTINUE READING
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