CNS infections, sepsis and risk of Parkinson's disease.

  title={CNS infections, sepsis and risk of Parkinson's disease.},
  author={Fang Fang and Karin Wirdefeldt and Andreas Jacks and Freya Kamel and Weimin Ye and Honglei Chen},
  journal={International journal of epidemiology},
  volume={41 4},
BACKGROUND Neuroinflammation may play an important role in the aetiology of Parkinson's disease (PD); however, little is known about infections in relation to future PD risk. METHODS We conducted a register-based nested case-control study in Sweden to examine infections of the central nervous system (CNS) and sepsis in relation to PD with 18,648 patients and 93,240 matched controls. We defined the index date as the date of first recorded PD diagnosis in the Swedish Patient Register. RESULTS… CONTINUE READING

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