CNS demyelination during anti–tumor necrosis factor alpha therapy

Abstract

Sirs: Tumor Necrosis Factor alpha (TNFalpha) is a cytokine released by activated monocytes, macrophages, and T-lymphocytes. It is involved in several processes, but plays an important role particularly in inflammation [1]. Its overproduction is implicated in a wide range of pathological conditions, including rheumatoid arthritis (RA) [2] and multiple… (More)
DOI: 10.1007/s00415-005-0055-1

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